Teriparatide
Approved medicineThe FDA has approved a version of this as a medicine, so it has been through large studies in people.
Also called Forteo / PTH 1-34 / Bonsity
An approved daily injection that builds bone in people with severe osteoporosis.
Can a doctor prescribe this?
Yes. Pharmacies are allowed to make it, so a doctor can write a prescription for it.
The FDA has approved a version of this as a medicine.
An approved prescription drug.
Official status: On the 503A bulks list. Checked 2026-08-04.
Lab suppliers we list: 2
Doses used in research
Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.
In human trials
See source wording
under the skin · daily · for 12 months
Sequential Therapies After Osteoanabolic TreatmentNot stated · NCT06164795
“Abaloparatide Injection (80 mcg).”
See source wording
by mouth · weekly · for 12 months
Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With TeriparatidePHASE2 · NCT02195895
“Weekly oral alendronate 70 mg for 12 months.”
See source wording
under the skin · daily
Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa).PHASE3 · NCT04750460
“Subcutaneous injections of study drug will be assigned immediately after parathyroidectomy (20 mcg), on the 1st (20 mcg) and 2nd (10 mcg) postoperative day..”
See source wording
by mouth · for 3 years
Effects of Teriparatide in the Treatment of Postmenopausal Women With OsteoporosisPHASE3 · NCT00670501
“Approximately 1000 mg/day of elemental calcium will be supplied as open-label oral supplement.”
20 mcg
daily · for 4 weeks
Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans?PHASE4 · NCT02090244
“Daily injections with teriparatide 20 µg (PTH 1-34 (Forteo®)) during four weeks.”
20 mcg
under the skin · daily
Treatment of Atraumatic Bone Marrow Edema With Denosumab and Teriparatide vs PlaceboPHASE4 · NCT01734824
“daily subcutaneous injection of teriparatide 20µg for three months.”
20 mcg
under the skin · daily · for 12 weeks
Teriparatide for Fracture Repair in HumansPHASE3 · NCT02091492
“Teriparatide 20 µg sc (subcutaneous injection) each day for 12 weeks.”
See source wording
under the skin · once a week
To Evaluate the Efficacy and Safety of SAL056 for Postmenopausal Women With Osteoporosis at High Fracture RiskPHASE3 · NCT07028320
“SAL056 (56.5μg).”
20 mcg
daily · for 12-24 months
Effect of Teriparatide on Fracture Healing in Patients With Incomplete Atypical Femur FracturesPHASE3 · NCT01896011
“Teriparatide 20 mcg.”
20 mcg
under the skin · daily · for 24 weeks
A Comparison of PF708 and Forteo in Osteoporosis PatientsPHASE3 · NCT03002428
“PF708 20 mcg once-daily subcutaneous injection for 24 weeks.”
See source wording
under the skin · daily
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic AcidPHASE4 · NCT03735537
“Any brand or preparation may be used to deliver the required dose of 5mg.”
5 mg
into a vein · daily
The Effect of Treatment With Teriparatide and Zoledronic Acid in Patients With Osteogenesis ImperfectaPHASE2 · NCT01679080
“yearly intravenous infusion of 5mg active zoledronic acid in 3 yr.”
See source wording
under the skin · every 12 hours · for 7 days
Teriparatide (Forteo) in the Treatment of Patients With Postoperative HypocalcemiaPHASE2 · NCT00623974
“Teriparatide 20 mcg.”
20 mcg
daily · for 12 months
12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)PHASE2 · NCT02025179
“Teriparatide 20 ug daily Sub-Q over 12 months.”
See source wording
Teriparatide on Maxillary Sinus Floor OsseointegrationPHASE4 · NCT06061354
“mixture of 20μg of teriparatide, 0.64ml of saline solution with 1g of Bio -Oss® or 1g of Bio-Oss® will be mixed with 0.72ml of saline solution..”
20 mg
daily
Fracture Recovery for Returning to Duty (Teriparatide STRONG)PHASE4 · NCT04589819
“Subjects in the teriparatide arm will receive a 20mg dose of the medication daily via self-injection..”
1000 mg/day
by mouth · once a week
A Study That Will Compare the Effect of Two Drugs on Participants With Low Bone Mass and a Recent Hip FracturePHASE4 · NCT00887354
“Approximately 500 to 1000 mg/day administered orally throughout study..”
See source wording
under the skin · once a day
“Patients were administered 20mcg of TP (Forsteo) subcutaneously once a day from the day between before 3months to after 3months about surgery..”
1 mg
under the skin
The Effects of Ibandronate or Teriparatide Therapy on Bone Histology and Biochemical Indices in Patients on Hemodialysis With Low Bone Mineral DensityPHASE4 · NCT00446589
“iv 1mg ibandronate monthly for one year.”
20 mcg
under the skin · once daily · for 6 months
Efficacy of WJ-derived Mesenchymal Stem Cells in Combination With Parathyroid Hormone for Vertebral Compression FracturePHASE2 · NCT05018637
“Other: subcutaneous injection of 20 µg teriparatide once daily for 6 months, followed by oral administration of anti-resorptive drug for 6 months.”
20 mcg
under the skin · for 18 months
A Study Using Imaging Technology to Measure Changes in Bone Structure After Treatment With TeriparatidePHASE4 · NCT00557310
“20 mcg teriparatide subcutaneous injection per day for 18 months, with possibility to continue for 24 months.”
20 mcg
daily
Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion SurgeryNA · NCT03770338
“20ug dosage daily injection, 1-month preoperative.”
20 mcg
under the skin · once daily · for 12 weeks
Chronotherapeutic Optimization of Teriparatide Administration in Postmenopausal OsteoporosisNA · NCT06951776
“Eligible participants will be randomly assigned (1:1) to either subcutaneous injection of 20 μg teriparatide at 08:00 a.m.”
See source wording
by mouth · every 6 hours · for 6 months
Effects of Teriparatide or Denosumab on Bone in Postmenopausal Women With OsteoporosisPHASE4 · NCT01753856
“Tetracycline (TET): Beginning 22 days prior to the biopsy procedure: Days 1, 2, 3 and 16, 17, 18: 250 mg TET will be taken orally every 6 hours; Days 4 through 15: TET will not be administered.”
100 IU/day
under the skin
Comparison Medications in the Treatment of Postmenopausal Women With OsteoporosisPHASE3 · NCT00542984
“salmon calcitonin 100 IU/day subcutaneous.”
See source wording
under the skin · once a month · for 12 months
Romosozumab/Denosumab Study for Premenopausal IOPPHASE2 · NCT04800367
“2 syringes of 105 MG/1.17 mL subcutaneous solution injected one after the other, once a month from study baseline through 11 month visit.”
20 mcg
under the skin
Pharmacokinetic and PHarmacodynamic Analysis and Evaluation of Teriparatide (PTH 1-34) Between SexesPHASE3 · NCT04921124
“Teriparatide, 20 µg Subcutaneous (S/C) per day.”
See source wording
under the skin · once a month · for 12 months
An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal WomenPHASE3 · NCT01796301
“Participants received 210 mg romosozumab administered by subcutaneous injection once a month for 12 months..”
See source wording
under the skin · once a day · for 12 months
µMRI of Therapeutic Intervention in Postmenopausal OsteoporosisPHASE4 · NCT01153425
“20 µg of Teriparatide will be self-injected subcutaneously once a day for 12 months and an MRI at 3T ('Virtual Bone Biopsy') will be performed at 0 and 12 months..”
20 mcg
under the skin · daily · for 24 weeks
Study to Evaluate Effect of Intranasal Teriparatide on Bone Mineral Density in Postmenopausal Women With Low BMDPHASE2 · NCT00624481
“20ug subcutaneous injection daily for 24 weeks.”
20 mcg
under the skin · daily
Study to Evaluate Effect of Intranasal Teriparatide on Serum P1NP, a Biomarker of Bone Formation, in Postmenopausal Women With Low Bone MassPHASE2 · NCT01604057
“20 mcg subcutaneous daily.”
In animal studies
See source wording
dogs · weekly · for 20 weeks
Synergistic effects of intermittent parathyroid hormone (1-34) and masticatory force for alveolar bone remodeling in the maxilla of dogs.Journal of stomatology, oral and maxillofacial surgery · 2026
“Methods In this exploratory pilot study, three male mongrel dogs were each assigned to a single dose group (n = 1 per group) and injected weekly for 20 weeks with vehicle (CON), 1.6 μg/kg PTH (PTH1.6), or 3.2 μg/kg PTH (PTH3.2).”
- Assessment of Teriparatide's Effect on Post-operative Functional Outcome and Fracture Healing.
Study in people
Journal of orthopaedic case reports · 2026
- Real-world effectiveness of denosumab compared to teriparatide in patients with severe osteoporosis.
Study in people
Frontiers in endocrinology · 2026
- Efficacy of once-weekly teriparatide versus alendronate in Chinese postmenopausal osteoporosis: a randomised, open-label, active-controlled, 48-week, multicentre phase III study.
Study in people
Journal of orthopaedic translation · 2026
- Synergistic effects of intermittent parathyroid hormone (1-34) and masticatory force for alveolar bone remodeling in the maxilla of dogs.
Dog study
Journal of stomatology, oral and maxillofacial surgery · 2026
- Bone response to intermittent parathyroid hormone (PTH) is both genetic and sex specific
Animal study, rats or mice
Journal not recorded · 2026
- Nutritional activation of the Nrf2-Pth1r axis by pyrroloquinoline quinone enhances peak bone mass and potentiates teriparatide in osteoporosis.
Animal study, rats or mice
Free radical biology & medicine · 2026
- Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation.
Animal study, rats or mice
Journal of the American Chemical Society · 2026
- Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice.
Animal study, rats or mice
Journal of cachexia, sarcopenia and muscle · 2025
- Smart polymersome carriers for osteoporosis treatment: Enhanced bone regeneration via targeted teriparatide delivery.
Lab dish study
Nanomedicine : nanotechnology, biology, and medicine · 2026
- Advancing hypoparathyroidism treatment: FDA approval of Palopegteriparatide as a promising orphan drug.
Annals of medicine and surgery (2012) · 2026
- Biochemical and clinical outcomes of once-daily teriparatide in refractory chronic hypoparathyroidism: A single-center experience.
Northern clinics of Istanbul · 2026
- Pharmacodynamics of sustained levels of PTH following palopegteriparatide treatment in adults with hypoparathyroidism.
Journal of the Endocrine Society · 2026
- Real-world evidence indicates romosozumab use is associated with a greater reduction in osteoporotic fractures than PTH (1-34) analogs in women.
Biology of sex differences · 2026
- Comparative Radiologic Outcomes of Romosozumab and Teriparatide in Osteoporotic Vertebral Fractures.
Journal of clinical medicine · 2026
- Comparison of Structurally Related Impurity Profiles in Teriparatide From Synthetic and Recombinant DNA Origin Using Liquid Chromatography-High Resolution Mass Spectrometry.
Rapid communications in mass spectrometry : RCM · 2026
- Consensus on the Treatment of Midshaft Clavicular Fractures in Collegiate Football Players: A Delphi Approach of Sports Medicine Teams.
Orthopaedic journal of sports medicine · 2026
- Teriparatide as an Adjunct in Managing Delayed Union of Long Bone Fractures: Insights from a Tertiary Care Center.
Annals of African medicine · 2026
- Bilateral healing of pseudofractures in hypophosphatasia with teriparatide: a case report.
Journal of medical case reports · 2026
- Comparative bone histomorphometry effects of combined denosumab and teriparatide vs monotherapy in postmenopausal women with osteoporosis: a randomized controlled trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
- Salvage of a Distal Ulnar Nonunion with Teriparatide Therapy.
Journal of hand surgery global online · 2025
- Early modification of blood glucose levels during teriparatide treatment in postmenopausal women with severe osteoporosis.
Journal of endocrinological investigation · 2025
- Advances in Parathyroid Hormone-based medicines.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
- Validation of a liquid chromatography-high-resolution mass spectrometry method to quantify peptide-related impurities in teriparatide.
Journal of pharmaceutical and biomedical analysis · 2025
- Palopegteriparatide (Yorvipath) for hypoparathyroidism.
The Medical letter on drugs and therapeutics · 2025
- Rebound Effect Following the Discontinuation of Palopegteriparatide.
Calcified tissue international · 2025
- Isolated Alkaline Phosphatase Elevation in Severe Osteoporosis Treatment: Implications of Teriparatide.
Journal of community hospital internal medicine perspectives · 2024
- Therapeutic advantage of teriparatide in very elderly patients with proximal femoral fractures: a functional and BMD analysis.
BMC musculoskeletal disorders · 2024
- Teriparatide
Journal not recorded · 2006
- Mechanisms limiting the long-term anabolic effects of teriparatide (PTH 1-34) on bone.
Review of earlier work
JBMR plus · 2026
- Management of a Complex Medial-End Clavicle Fracture With Hook Plate Fixation After Failed Prior Surgeries: A Case Report and Narrative Review of Surgical Options.
Review of earlier work
Case reports in orthopedics · 2026
- Teriparatide Therapy in Children with Hypoparathyroidism: A Systematic Review and Meta-Analysis.
Review of earlier work
Calcified tissue international · 2026
- Effect of teriparatide on improving fracture union in osteoporotic intertrochanteric fractures: A systematic review and meta-analysis.
Review of earlier work
World journal of orthopedics · 2026
- The impact of parathyroid hormone supplementation on dental implant osseointegration in osteoporotic subjects: A systematic review.
Review of earlier work
Journal of oral biosciences · 2026
- Immunogenicity risk assessment of peptide-related impurities identified in generic teriparatide products.
Review of earlier work
Frontiers in immunology · 2025
- Teriparatide for Guided Bone Regeneration in Craniomaxillofacial Defects: A Systematic Review of Preclinical Studies.
Review of earlier work
Current issues in molecular biology · 2025
- Teriparatide in postmenopausal osteoporosis: uncovering novel insights into efficacy and safety compared to other treatments - a systematic review and meta-analysis.
Review of earlier work
EFORT open reviews · 2024