PeptideSearch

Setmelanotide

Approved medicine

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The FDA has approved a version of this as a medicine, so it has been through large studies in people.

Compiled and reviewed by the PeptideSearch Editorial Team · Status checked 2026-08-04

Also called Imcivree / RM-493

An approved prescription drug for rare genetic forms of obesity.

Official status: Not nominated for 503A compounding · Checked 2026-08-04

Can a doctor prescribe this?

Small pharmacy (503A)
Never put forward to FDA
Large outsourcing facility (503B)
Never put forward to FDA

Approved as Imcivree for specific genetic conditions. Prescription-only.

503A is a pharmacy making a single prescription for one patient. 503B is a facility making batches. They are governed by separate lists. Where a category is shown, it is a position on the FDA's list of substances that have been put forward and are still being worked through — not the final list, which is set by rulemaking. Category 1 means the FDA does not plan to act against a pharmacy that makes it while the review runs.

Lab suppliers we list: 1

Doses used in research

Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.

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