Selank
Tested in peopleGet notified when the evidence changes.
It has been tested in people, but it is not an approved medicine. The studies are usually small.
Compiled and reviewed by the PeptideSearch Editorial Team · Status checked 2024-09-27
Also called TP-7 / Selank acetate / Tuftsin analogue
A Russian-developed peptide studied for anxiety. Most of the research is Russian-language.
Official status: Not nominated for 503A compounding · Checked 2024-09-27
Can a doctor prescribe this?
- Small pharmacy (503A)
- Never put forward to FDA
- Large outsourcing facility (503B)
- Never put forward to FDA
Left the FDA's restricted category in September 2024 when its nomination was withdrawn. It is not on the approved compounding list.
503A is a pharmacy making a single prescription for one patient. 503B is a facility making batches. They are governed by separate lists. Where a category is shown, it is a position on the FDA's list of substances that have been put forward and are still being worked through — not the final list, which is set by rulemaking. Category 1 means the FDA does not plan to act against a pharmacy that makes it while the review runs.
Lab suppliers we list: 14
Doses used in research
Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.
- Data from people, not a trial[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2008
- Animal study, rats or miceSelank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.
Bulletin of experimental biology and medicine · 2022
- Animal study, rats or miceThe Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.
Current reviews in clinical and experimental pharmacology · 2021
- Animal study, rats or miceMorphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.
Bulletin of experimental biology and medicine · 2020
- Animal study, rats or miceSelank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.
Bulletin of experimental biology and medicine · 2019
- Animal study, rats or miceEffect of Selank on Morphological Parameters of Rat Liver in Chronic Foot-Shock Stress.
Bulletin of experimental biology and medicine · 2019
- Animal study, rats or miceState of Colon Microbiota in Rats during Chronic Restraint Stress and Selank Treatment.
Bulletin of experimental biology and medicine · 2019
- Animal study, rats or miceEffect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress.
Bulletin of experimental biology and medicine · 2017
- Animal study, rats or miceEffect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons.
Bulletin of experimental biology and medicine · 2017
- Animal study, rats or miceStudying the Toxic Effects of Some Biologically Active Peptides on the Model of Mouse Embryonic Stem Cells.
Bulletin of experimental biology and medicine · 2017
- Animal study, rats or micePeptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2017
- Animal study, rats or micePeptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats.
Behavioural neurology · 2017
- Animal study, rats or miceSelank Inhibits Ethanol-Induced Hyperlocomotion and Manifestation of Behavioral Sensitization in DBA/2 Mice.
Bulletin of experimental biology and medicine · 2016
- Animal study, rats or mice[COMPARISON OF PHARMACOLOGICAL EFFECTS OF HEPTAPEPTIDE SELANK AFTER INTRANASAL AND INTRAPERITONEAL ADMINISTRATION TO BALB/c AND C57BL/6 MICE.]
Eksperimental'naia i klinicheskaia farmakologiia · 2016
- Animal study, rats or miceSelank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.
Frontiers in pharmacology · 2016
- Animal study, rats or miceThe temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action.
Molecular immunology · 2014
- Animal study, rats or miceEfficacy of peptide anxiolytic selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation.
Bulletin of experimental biology and medicine · 2014
- Animal study, rats or mice[Transcriptome alteration in hippocampus under the treatment of tuftsin analog Selank].
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova · 2013
- Animal study, rats or mice[Protective effect of selank on the model of mnestic function violation induced by pharmacological blockade of protein synthesis].
Eksperimental'naia i klinicheskaia farmakologiia · 2013
- Animal study, rats or mice[Effect of selank on the main carboxypeptidases in the rat nervous tissue].
Zhurnal evoliutsionnoi biokhimii i fiziologii · 2012
- Animal study, rats or mice[The role of opioid system in peculiarities of anti-anxiety effect of peptide anxiolytic selank].
Eksperimental'naia i klinicheskaia farmakologiia · 2012
- Animal study, rats or miceExpression of inflammation-related genes in mouse spleen under tuftsin analog Selank.
Regulatory peptides · 2011
- Animal study, rats or mice[Changes in expression of the genes for chemokines, cytokines, and their receptors in response to selank and its fragments].
Genetika · 2011
- Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.
Journal of clinical pharmacology · 2021
- Functional Connectomic Approach to Studying Selank and Semax Effects.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2020
- The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.
Drug testing and analysis · 2020
- Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.
Protein and peptide letters · 2018
- Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography.
Bulletin of experimental biology and medicine · 2017
- GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.
Frontiers in pharmacology · 2017
- [Optimization of the treatment of anxiety disorders with selank].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2015
- No abstract available, not yet classifiedThe influence of Selank on the parameters of the hemostasis system, lipid profile, and blood sugar level in the course of experimental metabolic syndrome.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2014
- [A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2014
- Review of earlier workTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
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