Ipamorelin
Very early researchGet notified when the evidence changes.
The research is at the earliest stage – mostly cells in a lab dish. It is far too early to say much.
Compiled and reviewed by the PeptideSearch Editorial Team · Status checked 2026-06-12
Also called NNC 26-0161 / Growth hormone secretagogue
A lab-made peptide studied for raising the body's own growth hormone. Research stalled early and there is no approved use.
The basics
- What is it?
- A lab-made peptide that nudges the body to release its own growth hormone.
- What do we know?
- In early tests it does raise growth hormone in the blood, without much effect on other hormones.
- What do we still not know?
- Whether raising growth hormone this way changes anything people care about. Development was dropped years ago.
Official status: Not nominated for 503A compounding · Checked 2026-06-12
Can a doctor prescribe this?
- Small pharmacy (503A)
- Never put forward to FDA
- Large outsourcing facility (503B)
- Category 2 — FDA flagged a safety concern
Not FDA approved and not on the 503A bulks list, so there is no legal compounding pathway.
503A is a pharmacy making a single prescription for one patient. 503B is a facility making batches. They are governed by separate lists. Where a category is shown, it is a position on the FDA's list of substances that have been put forward and are still being worked through — not the final list, which is set by rulemaking. Category 1 means the FDA does not plan to act against a pharmacy that makes it while the review runs.
Lab suppliers we list: 16
Doses used in research
Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.
- Study in peopleProspective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients.
International journal of colorectal disease · 2014
- Study in peoplePharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers.
Pharmaceutical research · 1999
- Animal study, rats or miceAttenuation of Visceral and Somatic Nociception by Ghrelin Mimetics.
Journal of experimental pharmacology · 2020
- Animal study, rats or miceEfficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus.
Journal of experimental pharmacology · 2012
- Animal study, rats or miceEfficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus.
The Journal of pharmacology and experimental therapeutics · 2009
- Animal study, rats or micePharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption.
Xenobiotica; the fate of foreign compounds in biological systems · 1998
- Studied in worms or fishThe influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus.
Animal reproduction science · 2024
- Testing of products for sale, not a health studyEvaluation of Research Grade Peptides Marketed Directly to Consumers Reveals Extensive Variability in Purity and Measured Abundance
2026
- Lab test method, not a health studyA new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
The Journal of sports medicine and physical fitness · 2026
- Lab test method, not a health studyGlycine-modified growth hormone secretagogues identified in seized doping material.
Drug testing and analysis · 2019
- Lab test method, not a health studyDoping control container for urine stabilization: a pilot study.
Drug testing and analysis · 2017
- Lab test method, not a health studySimplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry.
Journal of separation science · 2016
- Lab test method, not a health studyDetermination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and Ipamorelin.
Drug testing and analysis · 2015
- The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism.
Physiology & behavior · 2024
- Analysis of new growth promoting black market products.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2018
- A stable meta-carborane enables the generation of boron-rich peptide agonists targeting the ghrelin receptor.
Journal of peptide science : an official publication of the European Peptide Society · 2018
- Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor.
European journal of medicinal chemistry · 2018
- Structure-activity relationship for peptídic growth hormone secretagogues.
Drug testing and analysis · 2017
- Solid-phase extraction of small biologically active peptides on cartridges and microelution 96-well plates from human urine.
Drug testing and analysis · 2016
- Review of earlier workTherapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Frontiers in aging · 2026
- Review of earlier workInjectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.
The American journal of sports medicine · 2026
- Review of earlier workThe emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Frontiers in endocrinology · 2026
- Review of earlier workSafety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
Sports medicine (Auckland, N.Z.) · 2026
- Review of earlier workInjectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.
JBJS reviews · 2026
- Review of earlier workTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
- Review of earlier workPeptide Supplements and Their Therapeutic Applications in Sports Medicine.
The American journal of sports medicine · 2026
- Review of earlier workBeyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.
Translational andrology and urology · 2020
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What has happened so far
- 21 March 2025503B
FDA lists "Ipamorelin Acetate" — the acetate salt, the form pharmacies handle — under 503B Category 2: Bulk Drug Substances that Raise Significant Safety Risks. Outsourcing facilities are not to compound it. Read from the FDA 503B category document dated March 21, 2025.