IGF-1 DES
Very early researchGet notified when the evidence changes.
The research is at the earliest stage – mostly cells in a lab dish. It is far too early to say much.
Compiled and reviewed by the PeptideSearch Editorial Team · Status checked 2026-08-04
Also called DES(1-3) IGF-1 / Des-IGF-1
A shortened growth factor that acts quickly and locally. Used in lab research.
Official status: Not nominated for 503A compounding · Checked 2026-08-04
Can a doctor prescribe this?
- Small pharmacy (503A)
- Never put forward to FDA
- Large outsourcing facility (503B)
- Never put forward to FDA
Not approved and not on the compounding list.
503A is a pharmacy making a single prescription for one patient. 503B is a facility making batches. They are governed by separate lists. Where a category is shown, it is a position on the FDA's list of substances that have been put forward and are still being worked through — not the final list, which is set by rulemaking. Category 1 means the FDA does not plan to act against a pharmacy that makes it while the review runs.
Lab suppliers we list: 4
Doses used in research
Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.
- Animal study, rats or miceFunctional characterization of des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus.
Journal of neurophysiology · 2005
- Animal study, rats or miceDes(1-3)IGF-1 treatment normalizes type 1 IGF receptor and phospho-Akt (Thr 308) immunoreactivity in predegenerative retina of diabetic rats.
International journal of experimental diabesity research · 2003
- Animal study, rats or miceDifferential effects of des IGF-1 on Erks, AKT-1 and P70 S6K activation in mouse skeletal and cardiac muscle.
Molecular and cellular biochemistry · 2002
- Animal study, larger animalsReduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease.
Arthritis and rheumatism · 2000
- Animal study, rats or miceInvolvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors.
Endocrine · 1998
- Animal study, rats or miceThe effects of insulin-like growth factor (IGF)-1, IGF-2, and des-IGF-1 on neuronal loss after hypoxic-ischemic brain injury in adult rats: evidence for a role for IGF binding proteins.
Endocrinology · 1996
- Animal study, rats or miceA key functional role for the insulin-like growth factor 1 N-terminal pentapeptide.
The Biochemical journal · 1989
- Lab dish studyNecdin-E2F4 interaction provides insulin-sensitizing effect after weight loss induced by gastric bypass surgery.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2013
- Lab dish studyInsulin-like growth factor-1 downregulates nuclear factor kappa B activation and upregulates interleukin-8 gene expression induced by tumor necrosis factor alpha.
Biochemical and biophysical research communications · 2003
- Lab dish studyEffects of insulin-like growth factors on protein metabolism: why are some molecular variants more potent?
Biochemical Society symposium · 1989
- Lab dish studyInsulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.
The Biochemical journal · 1989
- Studied in plants, bacteria or fungi, not animals[Expression of mechano-growth factor in Escherichia coli and activity analysis].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2008
- Lab test method, not a health studyQuantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM · 2008
- Review of earlier workVitamin D and benign prostatic hyperplasia -- a review.
The Canadian journal of urology · 2013
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