CJC-1295
Tested in peopleGet notified when the evidence changes.
It has been tested in people, but it is not an approved medicine. The studies are usually small.
Compiled and reviewed by the PeptideSearch Editorial Team · Status checked 2026-06-12
Also called DAC:GRF / Modified GRF 1-29 / Tesamorelin analogue
A long-acting copy of the natural signal for growth hormone release, tested in small early studies in people. Not approved.
The basics
- What is it?
- A long-lasting lab-made copy of the brain signal that tells the body to release growth hormone.
- What do we know?
- Small early studies in people show it raises growth hormone for days after one dose.
- What do we still not know?
- Whether that leads to any real benefit, and what happens with repeated use over time.
Official status: Not nominated for 503A compounding · Checked 2026-06-12
Can a doctor prescribe this?
- Small pharmacy (503A)
- Never put forward to FDA
- Large outsourcing facility (503B)
- Never put forward to FDA
Not FDA approved and not on the 503A bulks list.
503A is a pharmacy making a single prescription for one patient. 503B is a facility making batches. They are governed by separate lists. Where a category is shown, it is a position on the FDA's list of substances that have been put forward and are still being worked through — not the final list, which is set by rulemaking. Category 1 means the FDA does not plan to act against a pharmacy that makes it while the review runs.
Lab suppliers we list: 16
Doses used in research
Taken word for word from the studies and trials listed on this page. This is not a recommendation and not a dose for anyone to take.
- Study in peopleActivation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2009
- Study in peopleProlonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
The Journal of clinical endocrinology and metabolism · 2006
- Horse studyAn immuno polymerase chain reaction screen for the detection of CJC-1295 and other growth-hormone-releasing hormone analogs in equine plasma.
Drug testing and analysis · 2019
- Animal study, rats or miceNeuronal M3 muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth.
Proceedings of the National Academy of Sciences of the United States of America · 2009
- Animal study, rats or micePulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog.
The Journal of clinical endocrinology and metabolism · 2006
- Animal study, rats or miceOnce-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.
American journal of physiology. Endocrinology and metabolism · 2006
- Lab dish studyAdvances in the detection of growth hormone releasing hormone synthetic analogs.
Drug testing and analysis · 2021
- Lab dish studyHuman growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog.
Endocrinology · 2005
- Testing of products for sale, not a health studyEvaluation of Research Grade Peptides Marketed Directly to Consumers Reveals Extensive Variability in Purity and Measured Abundance
2026
- Lab test method, not a health studyA new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
The Journal of sports medicine and physical fitness · 2026
- Lab test method, not a health studyAnalysis of growth hormone releasing hormone and its analogs in urine using nano liquid chromatography coupled with quadrupole/orbitrap mass spectrometry.
Journal of pharmaceutical and biomedical analysis · 2026
- Lab test method, not a health studyChromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples.
Journal of mass spectrometry : JMS · 2024
- Lab test method, not a health studyCationic exchange SPE combined with triple quadrupole UHPLC-MS/MS for detection of GHRHs in urine samples.
Analytical biochemistry · 2023
- Lab test method, not a health studyProbing for peptidic drugs (2-10 kDa) in doping control blood samples.
Analytical science advances · 2022
- Lab test method, not a health studyAn antibody-free, ultrafiltration-based assay for the detection of growth hormone-releasing hormones in urine at low pg/mL concentrations using nanoLC-HRMS/MS.
Journal of pharmaceutical and biomedical analysis · 2022
- Lab test method, not a health studyEarly detection of cannabinoids in biological samples based on their affinity interaction with the growth hormone secretagogue receptor.
Talanta · 2022
- Lab test method, not a health studyComparison of magnetic bead surface functionalities for the immunopurification of growth hormone-releasing hormones prior to liquid chromatography-high resolution mass spectrometry.
Journal of chromatography. A · 2020
- Lab test method, not a health studyA method for confirming CJC-1295 abuse in equine plasma samples by LC-MS/MS.
Drug testing and analysis · 2019
- Lab test method, not a health studyGlycine-modified growth hormone secretagogues identified in seized doping material.
Drug testing and analysis · 2019
- Lab test method, not a health studyQualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS.
Analytical and bioanalytical chemistry · 2016
- Lab test method, not a health studyThe study of doping market: How to produce intelligence from Internet forums.
Forensic science international · 2016
- Lab test method, not a health studyExpanded test method for peptides >2 kDa employing immunoaffinity purification and LC-HRMS/MS.
Drug testing and analysis · 2015
- Lab test method, not a health studyDetecting peptidic drugs, drug candidates and analogs in sports doping: current status and future directions.
Expert review of proteomics · 2014
- Lab test method, not a health studyDoping control analysis of seven bioactive peptides in horse plasma by liquid chromatography-mass spectrometry.
Analytical and bioanalytical chemistry · 2013
- Lab test method, not a health studyImmunoaffinity purification of peptide hormones prior to liquid chromatography-mass spectrometry in doping controls.
Methods (San Diego, Calif.) · 2012
- Lab test method, not a health studyIdentification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation.
Drug testing and analysis · 2010
- Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions.
Substance use & misuse · 2016
- Review of earlier workThe emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Frontiers in endocrinology · 2026
- Review of earlier workTherapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Frontiers in aging · 2026
- Review of earlier workInjectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.
The American journal of sports medicine · 2026
- Review of earlier workSafety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
Sports medicine (Auckland, N.Z.) · 2026
- Review of earlier workInjectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.
JBJS reviews · 2026
- Review of earlier workTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
- Review of earlier workPeptide Supplements and Their Therapeutic Applications in Sports Medicine.
The American journal of sports medicine · 2026
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